Unal Metin Tokat - Bilkent Univ. Ankara, Turkey#TAB#

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个人简介

I am a molecular biologist and geneticist in medical oncology. I analyze comprehensive genomic profiling data of the cancer patients to devise biomarker-guided targeted treatment approaches.

研究兴趣

论文共 18 篇作者统计合作学者相似作者

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Abstract 563: Targeting PDE4D Reinstates Toxic PARP Trapping Via Camp-Ros-dna Damage Axis and Restores the Efficacy of Standard of Care in Treatment-Refractory ER+ Breast Cancer

Ozge Saatci,Metin Cetin,Meral Uner,Unal M. Tokat,Ioulia Chatzistamou,Elodie Montaudon,Aytekin Akyol,Sercan Aksoy,Aysegul Uner,Elisabetta Marangoni,Mathew Sajish,Ozgur Sahin

Cancer Researchno. 6_Supplement (2024): 563-563

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Restoring the Efficacy of Standard of Care in Treatment-Refractory ER Plus Breast Cancer by Re-Activation of Camp-Ros-dna Damage Axis

Ozge Saatci,Metin Cetin,Meral Uner,Unal Metin Tokat,Ioulia Chatzistamou,Pelin Gulizar Ersan,Elodie Montaudon,Aytekin Akyol, Sercan Aksoy,Aysegul Uner,Elisabetta Marangoni,Sajish Mathew, Ozgur Sahin

CANCER RESEARCHno. 9 (2024)

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Alterations of Ceramide Synthesis Induce PD-L1 Internalization and Signaling to Regulate Tumor Metastasis and Immunotherapy Response

Wyatt Wofford,Jisun Kim,Dosung Kim,Alhaji H. Janneh,Han Gyul Lee, Cansu Atilgan,Natalia Oleinik,Mohamed Faisal Kassir,Ozge Saatci,Paramita Chakraborty,Unal Metin Tokat,Salih Gencer,Breege Howley,Philip Howe,Shikhar Mehrotra, Ozgur Sahin,Besim Ogretmen

CELL REPORTSno. 8 (2024)

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Abstract PO4-23-10: Restoring the Efficacy of Standard of Care in Treatment-Refractory ER+ Breast Cancer by Re-Activation of Camp-Ros-dna Damage Axis

Ozge Saatci,Metin Cetin,Meral Uner,Unal Metin Tokat,Ioulia Chatzistamou,Pelin Gulizar Ersan,Elodie Montaudon,Aytekin Akyol,Sercan Aksoy,Aysegul Uner,Elisabetta Marangoni,Sajish Mathew,Ozgur Sahin

Cancer Researchno. 9_Supplement (2024): PO4-23

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Targeting LINC00152 Activates Camp/ca2+/ferroptosis Axis and Overcomes Tamoxifen Resistance in ER+ Breast Cancer

Ozge Saatci,Rashedul Alam,Kim-Tuyen Huynh-Dam,Aynur Isik,Meral Uner,Nevin Belder,Pelin Gulizar Ersan,Unal Metin Tokat, Burge Ulukan,Metin Cetin, Kubra Calisir,Mustafa Emre Gedik,Hilal Bal, Ozlem Sener Sahin,Yasser Riazalhosseini,Denis Thieffry,Daniel Gautheret,Besim Ogretmen,Sercan Aksoy,Aysegul Uner,Aytekin Akyol,Ozgur Sahin

Cell Death and Diseaseno. 6 (2024)

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Toxic PARP Trapping Upon Camp-Induced DNA Damage Reinstates the Efficacy of Endocrine Therapy and CDK4/6 Inhibitors in Treatment-Refractory ER+ Breast Cancer

Ozge Saatci,Metin Cetin,Meral Uner,Unal Metin Tokat,Ioulia Chatzistamou,Pelin Gulizar Ersan,Elodie Montaudon,Aytekin Akyol,Sercan Aksoy,Aysegul Uner,Elisabetta Marangoni,Mathew Sajish,Ozgur Sahin

Nature Communicationsno. 1 (2023)

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Evaluation of the Relationship Between Aromatase/Sirtuin1 Interaction and Mirna Expression in Human Neuroblastoma Cells

Yasemin Kartal,Unal Metin Tokat,Pelin Kelicen-Ugur,Serkan Yilmaz,Sevilay Karahan,Murat Timur Budak

Current molecular pharmacology（2023）

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Abstract 3883: Overcoming Tamoxifen Resistance by Re-Activating Camp-Ca2+−ros-ferroptosis Axis in ER+ Breast Cancer

Rashedul Alam,Ozge Saatci,Meral Bugadyci Uner,Kim-Tuyen Huynh-Dam,Metin Cetin,Mustafa Emre Gedik,Nevin Belder,Hilal Bal,Unal Metin Tokat,Elisabetta Marangoni,Sercan Aksoy,Aysegul Uner,Aytekin Akyol,Ozgur Sahin

Cancer Researchno. 7_Supplement (2023): 3883-3883

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Overcoming tamoxifen resistance by re-activating cAMP-Ca2+-ROS-ferroptosis axis in ER plus breast cancer

CANCER RESEARCHno. 7 (2023)

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