Professor Arumugam’s research is primarily dedicated to unraveling neuronal cell death mechanisms in stroke and vascular dementia, with an emphasis on identifying novel therapeutic targets. Furthermore, his investigations extend to exploring the impact of intermittent metabolic switching on brain aging and related diseases. His contributions have appeared in journals such as Nature Medicine, Nature Neuroscience, Circulation, PNAS, Molecular Psychiatry, Theranostics, Cell Metabolism, and Nature Communications. With over 195 articles and three book chapters, his work has garnered over 22,000 citations (Google Scholar) and he maintains an h-index of 78.