Dr. Doré’s research pertains to studying new effective mechanisms that limit neuronal dysfunction associated with ischemic and hemorrhagic stroke, traumatic brain injury, Alzheimer disease (AD), aging, and various other neurological disorders. His objective is focused on understanding the protective role of heme metabolites in the brain using cellular/molecular techniques and various models of stroke, Alzheimer disease, and dementia. New knowledge is gained specifically by investigating the action and the role of activity of the heme oxygenase enzyme and its unique bioactive metabolites: carbon monoxide, iron, biliverdin, and bilirubin. He has also conducted pioneered work in the field of pro-inflammatory prostaglandins and the GPRR receptors. His overall goal is to slow down the progression of the disease and ultimately stop it.