Dr. Coffin has an active and well-funded research program that focuses on the prevention of healthcare-associated infections and vaccine-preventable diseases. Dr. Coffin is an active participant in numerous local, state and nation-wide public health programs that address such topics as the epidemiology and prevention of healthcare associated infections, pandemic influenza preparedness, and pediatric influenza. In addition, Dr. Coffin has worked on infectious diseases prevention projects in healthcare and community settings in Botswana, Ghana, Vietnam, Egypt, Greece and China.