基本信息
views: 129
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Stefano Rivella (PhD) holds the Kwame Ohene-Frempong Chair on Sickle Cell Anemia and is Professor of Pediatrics at the Children's Hospital of Philadelphia, Department of Pediatrics, Division of Hematology and in the Department of Cell and Molecular Biology Graduate Group (CAMB). He completed his studies at the University of Pavia in Italy and at Memorial Sloan Kettering Cancer Center in New York City, USA, then he opened his own lab at the Weill Cornell Medical College, NY, USA. Dr. Rivella has long-term expertise in the pathophysiology and genetics of thalassemia and in the use of lentiviral vectors for the cure of hemoglobinopathies. He has worked with many mouse models and he is familiar with their manipulation and with techniques to analyze erythropoiesis and gene expression as well as to achieve efficient gene transfer in vitro and in vivo. He generated the first adult mouse model of ß-thalassemia major and the first lentiviral vector that corrected the hemoglobin synthesis in these animals. He also characterized the role of seminal factors contributing to the morbidity and mortality in ß-thalassemia, Polycythemia vera, and hemochromatosis, such as the hormone that controls iron absorption (hepcidin), the phosphokynase Jak2, the erythroferrone and the role of macrophages in stress erythropoiesis.
Research Interests
Papers共 366 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Lucas Tricoli,Sunetra Sase,Julia Hacker,Vi Pham, Sidney Smith,Maxwell Chappell,Laura Breda,Stephanie Hurwitz,Naoto Tanaka,Carlo Castruccio Castracani,Amaliris Guerra, Zhongqi Hou,
bioRxiv : the preprint server for biology (2024)
AMERICAN JOURNAL OF HEMATOLOGY (2024)
Molecular Therapy - Methods & Clinical Developmentno. 1 (2024): 101222-101222
Vi Pham,Lucas Tricoli,Xinying Hong,Parith Wongkittichote,Carlo Castruccio Castracani,Amaliris Guerra,Lars Schlotawa,Laura A. Adang, Amanda Kuhs, Margaret M. Cassidy,Owen Kane, Emily Tsai,
biorxiv(2024)
American journal of hematologyno. 7 (2024): 1349-1359
MOLECULAR GENETICS AND METABOLISMno. 2 (2024)
Maxwell Chappell,Laura Breda, Danuta J. Jarocha, Tyler Papp,Amaliris Guerra,Kandace Gollomp,Stavros Glentis,Nattiya Teawtrakul, Megan Fedorky,Antonis Kattamis,Abdulmalik Osheiza,Valentina Ghiaccio,
MOLECULAR THERAPYno. 4 (2023): 36-37
Cited0Views0Bibtex
0
0
MOLECULAR THERAPYno. 4 (2023): 537-538
Cited0Views0Bibtex
0
0
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn