Simon Kelow - Fox Chase Cancer Center

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Bio

Research interest lies in computational biology techniques. Currently working in the lab of Roland Dunbrack focued on protein structure prediction and structural bioinformatics towards antibody design in silico. Also interested in focused educational outreach for black and latino students. Feel free to contact me @ simon.kelow@gmail.com

Research Interests

Papers共 12 篇Author StatisticsCo-AuthorSimilar Experts

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Corrigendum to “Computational design of nanomolar-binding antibodies specific to multiple SARS-CoV-2 variants by engineering a specificity switch of antibody 80R using RosettaAntibodyDesign (RAbD) results in potential generalizable therapeutic antibodies for novel SARS-CoV-2 virus” [Heliyon 9(4) (April 2023) e15032]

Nancy E. Hernandez,Wojciech Jankowski,Rahel Frick,Simon P. Kelow,Joseph H. Lubin,Vijaya Simhadri,Jared Adolf-Bryfogle,Sagar D. Khare,Roland L. Dunbrack,Jeffrey J. Gray,Zuben E. Sauna

Heliyonno. 8 (2023): e17901-e17901

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Candidate Variants in DNA Replication and Repair Genes in Early-Onset Renal Cell Carcinoma Patients Referred for Germline Testing

Elena V. Demidova,Ilya G. Serebriiskii,Ramilia Vlasenkova,Simon Kelow,Mark D. Andrake,Tiffiney R. Hartman,Tatiana Kent,James Virtucio,Gail L. Rosen,Richard T. Pomerantz,Roland L. Dunbrack,Erica A. Golemis,Michael J. Hall,David Y. T. Chen,Mary B. Daly,Sanjeevani Arora

BMC Genomics（2023）

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Computational Design of Nanomolar-Binding Antibodies Specific to Multiple SARS-CoV-2 Variants by Engineering a Specificity Switch of Antibody 80R Using RosettaAntibodyDesign (rabd) Results in Potential Generalizable Therapeutic Antibodies for Novel SARS-CoV-2 Virus

Nancy E. Hernandez,Wojciech Jankowski,Rahel Frick,Simon P. Kelow,Joseph H. Lubin,Vijaya Simhadri,Jared Adolf-Bryfogle,Sagar D. Khare,Jeffrey J. Gray,Zuben E. Sauna

Heliyon（2023）

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Computational design of nanomolar-binding antibodies specific to multiple SARS-CoV-2 variants by engineering a specificity switch of antibody 80R using RosettaAntibodyDesign (RAbD) results in potential generalizable therapeutic antibodies for novel SARS-CoV-2 virus (vol 9,e15032,2023)

Nancy E. Hernandez,Wojciech Jankowski,Rahel Frick,Simon P. Kelow,Joseph H. Lubin,Vijaya Simhadri,Jared Adolf-Bryfogle,Sagar D. Khare,Jeffrey J. Gray,Zuben E. Sauna

HELIYON（2023）

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Multi-segment preserving sampling for deep manifold sampler

Daniel Berenberg,Jae Hyeon Lee,Simon Kelow,Ji Won Park,Andrew Watkins,Vladimir Gligorijević,Richard Bonneau,Stephen Ra,Kyunghyun Cho

CoRR（2022）

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A penultimate classification of canonical antibody CDR conformations

Simon Kelow,Bulat Faezov,Qifang Xu,Mitchell Parker,Jared Adolf-Bryfogle,Roland L. Dunbrack

biorxiv（2022）

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Signatures of Defective DNA Repair and Replication in Early-Onset Renal Cancer Patients Referred for Germline Genetic Testing

Elena V. Demidova,Ilya G. Serebriiskii,Ramilia Vlasenkova,Simon Kelow,Mark D. Andrake,Tiffiney R. Hartman,Tatiana Kent,Richard T. Pomerantz,Roland L. Dunbrack,Erica A. Golemis,Michael J. Hall,David Y.T. Chen,Mary B. Daly,Sanjeevani Arora

crossref（2022）

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Function-guided Protein Design by Deep Manifold Sampling

Vladimir Gligorijević,Daniel Berenberg,Stephen Ra,Andrew Watkins,Simon Kelow,Kyunghyun Cho,Richard Bonneau

bioRxiv (2021)

Cited25Views0Bibtex

Hiding in Plain Sight: Structure and Sequence Analysis Reveals the Importance of the Antibody DE Loop for Antibody-Antigen Binding

Simon P. Kelow,Jared Adolf-Bryfogle,Roland L. Dunbrack

mAbs（2020）

Cited15Views0WOSBibtex

Mouse modeling and structural analysis of the p.G307S mutation in human cystathionine β-synthase (CBS) reveal effects on CBS activity but not stability

Sapna Gupta,Simon Kelow,Liqun Wang,Mark D Andrake,Roland L Dunbrack,Warren D Kruger

Journal of Biological Chemistry（2018）

Cited10Views0WOSBibtex

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