Her research interest in general is about decision support systems in medicine and more particularly on basic areas such as decision theory, clinical process modelling, artificial intelligence, probabilistic systems, biomedical statistics, knowledge acquisition. Application areas include support systems for diagnosis, therapy and monitoring, such as computerized guidelines, economic evaluation models based on decision analysis, telemedicine systems and workflow management within healthcare organizations. The main medical areas covered by such applications are stroke, chronic diseases, cardiovascular risk, motor and cognitive rehabilitation. The recent push toward personalized medicine has focused the latest applications on the "shared decision making" and "context-aware home-monitoring patients".