Joshi Shivangi

Constellation Pharmaceuticals

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论文共 14 篇作者统计合作学者相似作者

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1

Alexander M. Taylor, Chris Bailey, Lisa D. Belmont,Robert Campbell,Nico Cantone,Alexandre Cote,Terry D. Crawford,Richard Cummings,Kevin DeMent,Martin Duplessis,Megan Flynn,Andrew C. Good,Hon-Ren Huang,Shivangi Joshi,Yves Leblanc,Jeremy Murray,Christopher G. Nasveschuk,Adrianne Neiss,Florence Poy,F. Anthony Romero,Peter Sandy,Yong Tang,Vickie Tsui,Laura Zawadzke,Robert J. Sims, James E. Audia,Steven F. Bellon,Steven R. Magnuson,Brian K. Albrecht,Andrea G. Cochran

Journal of Medicinal Chemistry（2022）

引用4浏览0WOS引用

Development of a Gene-Editing Approach to Restore Vision Loss in Leber Congenital Amaurosis Type 10

Morgan L. Maeder,Michael Stefanidakis,Christopher J. Wilson,Reshica Baral,Luis Alberto Barrera,George S. Bounoutas,David Bumcrot,Hoson Chao,Dawn M. Ciulla,Jennifer A. DaSilva,Abhishek Dass,Vidya Dhanapal,Tim J. Fennell,Ari E. Friedland,Georgia Giannoukos,Sebastian W. Gloskowski, Alexandra Glucksmann,Gregory M. Gotta,Hariharan Jayaram,Scott J. Haskett,Bei Hopkins,Joy E. Horng,Shivangi Joshi,Eugenio Marco,Rina Mepani,Deepak Reyon,Terence Ta,Diana G. Tabbaa,Steven J. Samuelsson, Shen,Maxwell N. Skor,Pam Stetkiewicz,Tongyao Wang,Clifford Yudkoff,Vic E. Myer,Charles F. Albright,Haiyan Jiang

Nature medicine（2019）

引用473浏览0WOSNATURE引用

473

GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-Like

Shumei Wang,Vickie Tsui,Terry D. Crawford,James E. Audia,Daniel Burdick,Maureen H. Beresini,Alexandre Cote,Richard Cummings,Martin Duylessis,E. Megan Flynn,Michael C. Hewitt,Hon-Ren Huang,Hariharan Jayaram,Ying Jiang,Shivangi Joshi,Jeremy Murray,Christopher G. Nasveschuk,Eneida Pardo,Florence Poy,F. Anthony Romero,Yong Tang,Alexander M. Taylor,Jian Wang,Zhaowu Xu,Laura E. Zawadzke,Xiaoyu Zhu,Brian K. Albrecht,Steven R. Magnuson,Steve Bellon,Andrea G. Cochran

Journal of Medicinal Chemistry（2018）

引用11浏览0WOS引用

TAF1-BD2 in complex with Cpd27 (6-(but-3-en-1-yl)-4-(1-methyl-6-(morpholine-4-carbonyl)-1H-benzo[d]imidazol-4-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one)

Shumei Wang,V. Tsui,Terry D Crawford,J. Audia, D. Burdick,Maureen Beresini,Alexandre Côté,Richard D. Cummings, M. Duplessis, E. M. Flynn, M. Hewitt,Hon-Ren Huang,H. Jayaram, Ying Jiang,Shivangi Joshi,Jeremy Murray,C. Nasveschuk, E. Pardo,F. Poy,F. A. Romero, Yong Tang,Alexander M Taylor, Jian Wang,Zhaowu Xu, L. Zawadzke, Xiaoyu Zhu,B. Albrecht,Steven Magnuson, S. Bellon,Andrea G Cochran

semanticscholar（2018）

引用0浏览0引用

GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2)

Terry D Crawford, James E Audia,Steve Bellon,Daniel J Burdick,Archana Bommi-Reddy,Alexandre Côté,Richard T Cummings,Martin Duplessis,E Megan Flynn,Michael Hewitt,Hon-Ren Huang,Hariharan Jayaram,Ying Jiang,Shivangi Joshi,James R Kiefer,Jeremy Murray,Christopher G Nasveschuk, Arianne Neiss,Eneida Pardo,F Anthony Romero,Peter Sandy,Robert J Sims,Yong Tang,Alexander M Taylor,Vickie Tsui,Jian Wang,Shumei Wang,Yongyun Wang,Zhaowu Xu,Laura Zawadzke,Xiaoqin Zhu,Brian K Albrecht,Steven R Magnuson,Andrea G Cochran

ACS medicinal chemistry letters（2017）

引用19浏览0WOS引用

Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials

Brian K Albrecht,Victor S Gehling,Michael C Hewitt,Rishi G Vaswani,Alexandre Côté,Yves Leblanc,Christopher G Nasveschuk,Steve Bellon,Louise Bergeron,Robert Campbell,Nico Cantone, Michael R Cooper,Richard T Cummings,Hariharan Jayaram,Shivangi Joshi,Jennifer A Mertz,Adrianne Neiss,Emmanuel Normant,Michael O'Meara,Eneida Pardo,Florence Poy,Peter Sandy,Jeffrey Supko,Robert J Sims,Jean-Christophe Harmange,Alexander M Taylor, James E Audia

JOURNAL OF MEDICINAL CHEMISTRY（2016）

引用162浏览0WOS引用

162

ヒト臨床試験候補であるブロモドメインおよび末端外(BET)ファミリーのベンゾイソキサゾロアゼピン阻害剤(CPI‐0610)の同定

Kim Brian,S Gehling Victor,C Hewitt Michael,G Vaswani Rishi,Alexandre Côté,Yves Leblanc,Glidewell Christopher,Bellon Steve,Bergeron Louise,Campbell Robert,Cantone Nico,R Cooper Michael, T Cummings Richard,Jayaram Hariharan,Joshi Shivangi,A Mertz Jennifer,Neiss Adrianne,Normant Emmanuel,O’Meara Michael,Eneida Pardo,Florence Poy,Sandy Peter,Jeffrey Supko,Sims Robert J.,Harmange Jean‐Christophe,M Taylor Alexander,E. A. James

Journal of medicinal chemistryno. 4 (2016): 1339

引用0浏览0引用

Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains

Alexander M Taylor,Rishi G Vaswani,Victor S Gehling,Michael C Hewitt,Yves Leblanc,James E Audia,Steve Bellon,Richard T Cummings,Alexandre Côté,Jean-Christophe Harmange,Hari Jayaram,Shivangi Joshi,Jose M Lora,Jennifer A Mertz,Adrianne Neiss,Eneida Pardo,Christopher G Nasveschuk,Florence Poy,Peter Sandy,Jeremy W Setser,Robert J Sims,Yong Tang,Brian K Albrecht

ACS medicinal chemistry letters（2016）

引用27浏览0WOS引用

Development of Methyl Isoxazoleazepines As Inhibitors of Bet (vol 25, Pg 1842, 2015)

Michael C. Hewitt,Yves Leblanc,Victor S. Gehling,Rishi G. Vaswani,Alexandre Cote,Christopher G. Nasveschuk,Alexander M. Taylor,Jean-Christophe Harmange,James E. Audia,Eneida Pardo,Rich Cummings,Shivangi Joshi,Peter Sandy,Jennifer A. Mertz,Robert J. Sims,Louise Bergeron,Barbara M. Bryant,Steve Bellon,Florence Poy,Hariharan Jayaram,Yong Tang,Brian K. Albrecht

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2015）

引用0浏览0引用

Abstract A20: A Leukemic Model of Acquired Resistance to BET Inhibition Reveals a Role for CBP/EP300 Bromodomains in the Regulation of C-Myc Expression

Andrew R. Conery,Richard C. Centore,Charlie Hatton,Adrianne Neiss,Hon-Ren Huang,Patricia J. Keller,Alexander M. Taylor,Alexandre Cote,Michael C. Hewitt,Christopher G. Nasveschuk,Yves Leblanc, Shihua Yao,Eneida Pardo,Laura Zawadzke,Florence Poy,Hari Jayaram,Shivangi Joshi,Peter Sandy,Anthony Romero,Terry Crawford,Richard Pastor,Tommy Lai,Kevin Chen,Jian Wang,Steven Magnuson,Brian K. Albrecht,Steve Bellon,Barbara M. Bryant,Robert J. Sims

Molecular cancer research（2015）

引用0浏览0引用

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作者统计

#Papers: 14

#Citation: 1065

H-Index: 9

G-Index: 10

Sociability: 5

Diversity: 2

Activity: 2

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