Scott H. Kaufmann, M.D., Ph.D., is an oncologist at Mayo Clinic who also conducts research to study what happens when cancer cells are treated with targeted anti-cancer agents. Research in Dr. Kaufmann's Anticancer Drug Action Laboratory focuses on two major questions: 1) What is the biochemical basis for cell killing when it occurs, and 2) What can happen to cancer cells to make them resistant to these treatments. Within the context of these broad questions, Dr. Kaufmann's lab applies a wide range of biochemistry, cell biology and molecular biology approaches to a series of projects.