S. Chia’s main research interest lie in translational research and in clinical research. His translational research is primarily in breast cancer, with a focus on assessment and validation of new and novel prognostic and predictive factors. He has numerous peer reviewed grants as the lead independent PI, as well has published several peer reviewed papers as the first author in this area. His clinical research involves phase I-III clinical trials as well as population based outcomes research. Has been the lead PI for a large international phase III trial (see below) which has been published (J Clin Oncol 2008;26:1664-1670) as well as the lead PI on two investigator led phase II trials in neoadjuvant therapy of locally advanced breast cancer. He is also involved in phase I-II trials in investigational new drugs as well as in head and neck cancer.