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个人简介
Dr Sladek's scientific contributions centre on establishing the role of gene transcription networks in complex traits. He identified key physiological roles for the orphan nuclear receptor ERRalpha in regulating the balance between lipolysis and lipogenesis and ERRbeta in regulating development of the chorion and trophoblast. He has developed methods to identify transcriptional networks de novo in panels of recombinant congenic mouse strains and to characterize transcriptional effects of cis-regulatory genetic variants that underlie complex genetic traits. Most recently, he collaborated with Drs Froguel, Polychronakos, Posner and Prentki to complete the first genome-wide association study (GWAS) to identify risk loci for type 2 diabetes.
研究兴趣
论文共 211 篇作者统计合作学者相似作者
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Nature Communicationsno. 1 (2024): 1-11
Soo Heon Kwak, Ryan B. Hernandez-Cancela,Daniel A. DiCorpo,David E. Condon,Jordi Merino,Peitao Wu,Jennifer A. Brody,Jie Yao,Xiuqing Guo,Fariba Ahmadizar,Mariah Meyer,Murat Sincan,Josep M. Mercader,Sujin Lee,Jeffrey Haessler,Ha My T. Vy,Zhaotong Lin, Nicole D. Armstrong,Shaopeng Gu,Noah L. Tsao,Leslie A. Lange, Ningyuan Wang,Kerri L. Wiggins,Stella Trompet,Simin Liu,Ruth J. F. Loos,Renae Judy,Philip H. Schroeder,Natalie R. Hasbani,Maxime M. Bos,Alanna C. Morrison,Rebecca D. Jackson,Alexander P. Reiner,JoAnn E. Manson,Ninad S. Chaudhary,Lynn K. Carmichael,Yii-Der Ida Chen,Kent D. Taylor,Mohsen Ghanbari,Joyce van Meurs,Achilleas N. Pitsillides,Bruce M. Psaty,Raymond Noordam,Ron Do,Kyong Soo Park,J. Wouter Jukema,Maryam Kavousi,Adolfo Correa,Stephen S. Rich,Scott M. Damrauer,Catherine Hajek,Nam H. Cho,Marguerite R. Irvin,James S. Pankow,Girish N. Nadkarni,Robert Sladek,Mark O. Goodarzi,Jose C. Florez,Daniel I. Chasman,Susan R. Heckbert,Charles Kooperberg,Josee Dupuis,Rajeev Malhotra,Paul S. de Vries,Ching-Ti Liu,Jerome I. Rotter,James B. Meigs
BIOINFORMATICSno. 5 (2024)
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDSno. 3 (2024)
Vanessa Yu,Fiona Yong, Angellica Marta,Sanjay Khadayate,Adrien Osakwe,Supriyo Bhattacharya,Sneha S. Varghese,Pauline Chabosseau, Sayed M. Tabibi,Keran Chen,Eleni Georgiadou,Nazia Parveen,Mara Suleiman, Zoe Stamoulis,Lorella Marselli,Carmela De Luca,Marta Tesi, Giada Ostinelli,Luis Delgadillo-Silva,Xiwei Wu,Yuki Hatanaka,Alex Montoya,James Elliott,Bhavik Patel, Nikita Demchenko,Chad Whilding,Petra Hajkova, Pavel Shliaha,Holger Kramer,Yusuf Ali,Piero Marchetti,Robert Sladek,Sangeeta Dhawan,Dominic J. Withers,Guy A. Rutter,Steven J. Millership
Circulationno. Suppl_1 (2024)
NANOETHICSno. 2 (2024)
MACHINE LEARNING WITH APPLICATIONS (2024)
Life sciences (2023): 121436-121436
Alisa Manning,Magdalena Sevilla-González,Kirk Smith, Ningyuan Wang,Aubrey Jensen,Elizabeth Litkowski,Hyunkyung Kim,Daniel DiCorpo,Kenneth Westerman,Jinrui Cui,Ching-Ti Liu,Chenglong Yu,John McNeil,Paul Lacaze,Kyong-Mi Chang,Phil Tsao,Lawrence Phillips,Mark Goodarzi,Rob Sladek,Jerome Rotter,Josee Dupuis,Jose Florez,Jordi Merino,James Meigs,Jin Zhou,Sridharan Raghavan,Miriam Udler
Research square (2023)
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作者统计
#Papers: 212
#Citation: 24596
H-Index: 58
G-Index: 141
Sociability: 8
Diversity: 3
Activity: 26
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