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个人简介
Robbie Majzner is an Assistant Professor of Pediatrics in the Division of Hematology and Oncology. Dr. Majzner attended Harvard Medical School, where he developed an interest in pediatric oncology. He completed his residency training in pediatrics at New York Presbyterian-Columbia and fellowship training in pediatric hematology-oncology at Johns Hopkins and the National Cancer Institute. During his fellowship, he cared for some of the first pediatric patients to receive CD19 chimeric antigen receptor (CAR) T cells, children with B cell acute lymphoblastic leukemia (B-ALL) who often had no other therapeutic option. Witnessing the success of CAR T cells in these patients drove Dr. Majzner to the laboratory, where he focuses on extending the use of CAR T cells to solid tumors. He has generated and optimized novel receptors to recognize antigens over-expressed on pediatric solid tumors such as GD2 (Mount/Majzner et al., Nature Medicine, 2018) B7-H3 (Majzner et al., Clinical Cancer Research, 2019), and ALK (Walker/Majzner et al., Molecular Therapy, 2017). Current work focuses on imparting multi-specificity to CAR T cells and optimizing these receptors to enhance their efficacy when the amount of target (antigen density) is limiting (Majzner et al., Cancer Discovery, 2020). By drawing on state of the art bioengineering techniques, the Majzner Laboratory focuses on enhancing the potency and specificity of CAR T cells for children with cancer.
研究兴趣
论文共 132 篇作者统计合作学者相似作者
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Jasia Mahdi,Jorg Dietrich,Karin Straathof,Claire Roddie,Brian J. Scott,Tom Belle Davidson,Laura Prolo,Tracy T. Batchelor,Cynthia J. Campen,Kara L. Davis,Juliane Gust,Michael Lim,Robbie G. Majzner,Julie R. Park,Sonia Partap,Sneha Ramakrishna,Rebecca Richards,Liora Schultz,Nicholas A. Vitanza,Leo D. Wang,Crystal L. Mackall,Michelle Monje
NEURO-ONCOLOGY (2024)
Pablo Domizi,Jolanda Sarno,Astraea Jager,Milton Merchant, Kaithlen Zen B. Pacheco,Sean A. Yamada-Hunter,Maria Caterina Rotiroti,Yuxuan Liu,Reema Baskar,Warren D. Reynolds,Brian J. Sworder, Bita Sahaf,Sean C. Bendall, Charles G. Mullighan,Ash A. Alizadeh, Allison B. Leahy,Regina M. Myers,Bonnie Yates, Hao-Wei Wang, Nirali N. Shah,Robbie G. Majzner, Crystal L. Mackall,Stephan A. Grupp, David M. Barrett,Elena Sotillo, Kara L. Davis
biorxiv(2024)
Sneha Ramakrishna,Anna Geraghty,Zinaida Good,Moksha Desai,Rebecca Mancusi,Jasia Mahdi,Kun Wei Song,Zachary Ehlinger, Yiyun Chen,Mark Hamilton, Skyler Rietberg,Robbie Majzner,Liora Schultz, Becky Richards,Jennifer Kamens,Vali Barsan,Cynthia Campen,Sonia Partap,Jennifer Moon,Christina Baggott, Michael Kunick,Michelle Fujimoto,Amy Li, Sneha Jariwala,Sharon Mavroukakis,Emily Egeler,Ashley Jacobs,Courtney Erickson,Snehit Prabhu,Kara Davis,Steven Feldman,Bita Sahaf,Crystal Mackall,Michelle Monje
Neuro-Oncologyno. Supplement_8 (2024)
Transplantation and cellular therapy (2024)
Marta T. Borowska, Liu D. Liu,Nathanael A. Caveney,Kevin M. Jude, Won-Ju Kim,Takeya Masubuchi,Enfu Hui,Robbie G. Majzner,K. Christopher Garcia
SCIENCE IMMUNOLOGYno. 100 (2024)
Pablo Domizi,Jolanda Sarno,Astraea Jager,Milton Merchant, Kaithlen Pacheco,Sean Yamada-Hunter,Maria Caterina Rotiroti,Yuxuan Liu,Reema Baskar,Warren Reynolds,Brian Sworder,Bita Sahaf,Sean Bendall,Charles Mullighan,Ash Alizadeh,Allison Leahy,Regina Myers,Stephan Grupp,Robbie Majzner,David Barrett,Elena Sotillo,Kara Davis
Cancer Researchno. 17_Supplement (2024)
Pablo Domizi,Jolanda Sarno,Astraea Jager,Milton Merchant, Kaithlen Pacheco,Sean Yamada-Hunter,Maria Caterina Rotiroti,Yuxuan Liu,Reema Baskar,Warren Reynolds,Brian Sworder, Bita Sahaf,Sean Bendall,Charles Mullighan,Ash Alizadeh,Allison Leahy,Regina Myers,Stephan Grupp,Robbie Majzner, David Barrett,Elena Sotillo,Kara Davis
CANCER RESEARCHno. 17 (2024)
Michelle Monje,Jasia Mahdi,Robbie G. Majzner,Kristen W. Yeom,Liora M. Schultz,Rebecca M. Richards,Valentin Barsan,Kun-Wei Song,Jennifer L. Kamens,Christina Baggott,Michael Kunicki, Andrew Kean Seng Lim,Agnes Reschke,Sharon Mavroukakis,Emily Egeler,Jennifer Moon,Shabnum Patel,Harshini Chinnasamy,Courtney Erickson,Ashley Jacobs,Allison K. Duh,Skyler P. Rietberg,Ramya Tunuguntla,Dorota Klysz,Carley Fowler,Sean Green, Barbara Beebe, C. Carr,Michelle Fujimoto,Annie Brown, A. Townsend Peterson, Catherine McIntyre, Aman Siddiqui, Nadia Lepori‐Bui,Katlin Villar, Khanh Tien Nguyen Pham, Robert Bove, Eric Musa,Warren Reynolds,Alex Kuo,Snehit Prabhu,Lindsey Rasmussen,Timothy T. Cornell,Sonia Partap,Paul Fisher,Cynthia Campen,Gerald A. Grant,Laura M. Prolo,Xiaobu Ye,Bita Sahaf,Kara L. Davis,Steven A. Feldman,Sneha Ramakrishna,Crystal L. Mackall
Neuro-oncologyno. Supplement_4 (2024): 0-0
Sean A. Yamada-Hunter,Johanna Theruvath,Brianna J. Mcintosh,Katherine A. Freitas, Frank Lin,Molly T. Radosevich,Amaury Leruste,Shaurya Dhingra,Naiara Martinez-Velez,Peng Xu,Jing Huang,Alberto Delaidelli,Moksha H. Desai,Zinaida Good, Roel Polak, Audre May,Louai Labanieh,Jeremy Bjelajac,Tara Murty,Zach Ehlinger,Christopher W. Mount, Yiyun Chen,Sabine Heitzeneder,Kristopher D. Marjon,Allison Banuelos,Omair Khan,Savannah L. Wasserman,Jay Y. Spiegel,Sebastian Fernandez-Pol,Calvin J. Kuo,Poul H. Sorensen,Michelle Monje,Robbie G. Majzner,Irving L. Weissman,Bita Sahaf,Elena Sotillo,Jennifer R. Cochran,Crystal L. Mackall
Natureno. 8016 (2024): 457-465
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作者统计
#Papers: 132
#Citation: 6398
H-Index: 29
G-Index: 63
Sociability: 7
Diversity: 3
Activity: 281
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