Rob Wolthuis

Genes that govern cell division, maintain the stability of the genome or control cell death are often mutated in cells from which cancer originates. We aim to understand genetic cancer predispositions by a combination of basic and translational research. Investigated are the principle biological mechanisms of cancer cell proliferation, ways to detect cancer at the earliest stage (biomarkers, liquid biopsies) and new strategies to selectively kill cancer cells while protecting healthy cells.