Dr. Silver's research interests center on scleroderma and, in particular, scleroderma lung disease, now a major cause of death among patients with scleroderma. He and his colleagues were the first to utilize bronchoalveolar lavage (BAL) to characterize scleroderma lung disease. He played an instrumental role in the design and development of the Scleroderma Lung Study I and II. Dr. Silver helped to initiate and develop MUSC’s pulmonary hypertension center and sarcoidosis center. Dr. Silver serves as associate director of a multidisciplinary clinical research center (MCRC) for the study of rheumatic diseases in African-Americans funded by NIAMS. Dr. Silver’s clinical interests include scleroderma and scleroderma-related conditions, as well as childhood rheumatic diseases.