基本信息
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Career Trajectory
Bio
Dr. R. Jude Samulski received his PhD in medical microbiology and immunology from the University of Florida. His graduate work (1978-82) demonstrated the first use of AAV as a viral vector and culminated in the development of the first FDA AAV drug approved for blindness. Dr. Samulski has worked with AAV for 40 years, and for 25 years, he was director of the University of North Carolina Gene Therapy Center where he has focused on development of AAV as a gene delivery system, which has led to the first long-term gene delivery in muscle, brain and other tissues. His development of novel AAV variants as alternative vectors and improvements in AAV production facilitated the first clinical trial for gene delivery to the brain and his development of the first chimeric AAV facilitated gene delivery for muscular dystrophy. He continues to derive delivery systems for safe, efficient use in human gene therapy to facilitate the progression and translation of gene therapy research into clinical trials for treatment of human diseases. Dr. Samulski has advanced therapeutics into human clinical trials for hemophilia, Duchenne muscular dystrophy, giant axonal neuropathy, Pompe disease and heart failure. He holds more than 200 patents related to AAV technology.
Research Interests
Papers共 594 篇Author StatisticsCo-AuthorSimilar Experts
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Journal of the American Veterinary Medical Associationpp.1-12, (2024)
Molecular therapy Methods & clinical developmentno. 1 (2024): 101211-101211
Frontiers in Veterinary Science (2023)
Molecular therapy Methods & clinical development (2023): 30-47
Joerg Votteler, Alma Chanelo, D'Shawna Burwell,Thao Tran, Youjun Chen,Charles Krause,Lorne Celentano,Abbie Svancarek, Haley Grooms, Alea Powell, Kelsey Higgins,Angela Mote, Layth Awartani,Rohini Sheth,Christine Daniels, Rachel Hedinger,Alan Curtis,Audry Fernandez,Shari N. Gordon,Xintao Zhang,Scott Hammond,Chengwen Li,Anna Tretiakova,Jude Samulski
MOLECULAR THERAPYno. 4 (2023): 101-102
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Audry Fernandez, Rachel Hedinger, Alea Powell, Haley Grooms,Rohini Sheth, Layth Awartani,Dylan Southers,Alan Curtis,Angela Mote,Sherif Gabriel,Anna Tretiakova,Shari Gordon,R. Jude Samulski
MOLECULAR THERAPYno. 4 (2023): 112-112
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Ferzin Sethna, Monika Mittal, Laura Buczek Orenstein,Joerg Votteler,Lester Suarez,Scott Hammond,Anna P. Tretiakova,R. Jude Samulski
MOLECULAR THERAPYno. 4 (2023): 95-95
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Youjun Chen,Ferzin Sethna,Abbie Svancarek, Cody L. Evans, Joshua T. Hatfield,Timothy D. Henry,Eugene Chung, Sheila Mikhail,Roger J. Hajjar,Anna P. Tretiakova,R. Jude Samulski
MOLECULAR THERAPYno. 4 (2023): 625-625
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P. Thampi,K. A. Seabaugh,L. M. Pezzanite,C. R. Chu,J. N. Phillips,J. C. Grieger,C. W. McIlwraith,R. J. Samulski, L. R. Goodrich
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Author Statistics
#Papers: 597
#Citation: 44271
H-Index: 108
G-Index: 200
Sociability: 7
Diversity: 3
Activity: 47
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