Our laboratory is interested in the role of receptors in the regulation of nerve cell function.We are particularly interested in the role of cytokines in nerve cell biology.The effects of cytokines on neural stem cell development and in the genesis of chronic pain syndromes are of current interest.We study these phenomena using biochemistry,molecular biology,electrophysiology,mouse genetics and imaging.Projects in our laboratory involve the development of drugs that act on cytokine receptors as well as the molecular basis for pain in osteoarthritis and diabetic neuropathy.