He directs the Tobacco Research Laboratory at the Harvard Chan School, where the design and potential for dependence of tobacco products are assessed. Studies examine the impact of dependence potential on product use and individual risk, to inform policy and other interventions to control tobacco harms. Current research uses conventional and innovative strategies to evaluate new and novel tobacco products. Examples of these products include modified risk tobacco products such as e-cigarettes; reduced ignition propensity cigarettes; hookah (tobacco waterpipe); and novel smokeless tobacco products such as snus. Clinical research methods are used to evaluate the influence of tobacco product design features on consumer responses, and their role in promoting initiation or maintenance of use among targeted populations. Findings have been used to inform tobacco control policy, develop resources for communicating risks of tobacco products, and to enhance understanding of factors that contribute to tobacco dependence.