All of Prof. Kyes' research, teaching and service activities have a strong international focus. Since coming to the University of Washington, he has been responsible for helping to establish collaborative programs in a number of countries, including Indonesia, Nepal, China, Thailand, Bangladesh, Democratic Republic of Congo, Mexico, and India, with developing programs in Laos, Vietnam, Cambodia, and Brazil. These partnerships involve joint research, annual field training programs ("Field Course in Conservation Biology & Global Health") for local university students and professionals, and community outreach education programs for school children, K-12.

Although splitting his time among the program countries, Prof. Kyes has worked in Indonesia the longest (over 25 years) collaborating with Bogor Agricultural University (IPB) and their Primate Research Center (PSSP) as well as a number of other institutions including, Sam Ratulangi Univ., Udayana Univ., Gadjah Mada Univ., Univ. of Indonesia, Sebelas Maret Univ., Andalas Univ., Hasanuddin Univ., Tadulako Univ., Univ. of Dumogo Kotamobagu, Papua State Univ., and a number of government offices and NGOs. In addition to the research, Prof. Kyes and his colleagues conduct annual field courses in Conservation Biology & Global Health on Tinjil Island, Banten, Java (since 1991) and at the Tangkoko Nature Reserve, North Sulawesi (since 1998).