While the need for space exploration expands, the effects of spaceflight and space conditions on human physiology are poorly understood. The goal of my research is to understand the influence of spaceflight conditions (microgravity, hypergravity, ionizing radiation) on host-pathogen interactions using Drosophila melanogaster and Serratia marcescens. This work will help us to better understand how space changes not just human immunity, but also the pathogens that interact with the immune system.