Pratip K Chattopadhyay

T-cell immunity is orchestrated by a complex set of proteins, associated with function, maturation, and homing (among other things). This complexity has largely precluded the identification of changes, early in the immune response, that predict vaccine efficacy or disease outcome. To unravel this complexity, I develop and apply tools for highly multiplexed analysis of single cells, including polychro. flow cytometry, CyTOF, and 96-parameter single cell PCR. I apply these to HIV and EBV studies.