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个人简介
Dr. Phil Kym has been Executive Director of Drug Discovery Science & Technology since 2019 and Head of the AbbVie Medicinal Chemistry Leadership Team since 2018. In his career at Abbott/AbbVie, Phil has led teams that have discovered clinical candidates in the Neuroscience, Immunology, Oncology, Virology, Metabolic Disease, Cystic Fibrosis, and Pain therapeutic areas. He is an inventor of Foslevodopa/Foscarbidopa subcutaneous continuous infusion therapy for the symptomatic treatment of advanced Parkinson’s Disease. Phil received a B.A. in Chemistry from Goshen College, a Ph.D. in Organic Chemistry from the University of Illinois at Urbana-Champaign, and completed an American Cancer Society Postdoctoral Fellowship at the University of Texas at Austin before starting his career at Abbott/AbbVie in 1996. Phil has served on the ACS MEDI Long Range Planning Committee (2018-2020), the organizing committee for the 2022 National Medicinal Chemistry Symposium, and will be the Chair of the 2023 Gordon Research Conference on Natural Products and Bioactive Compounds.
• Head, AbbVie Medicinal Chemistry Leadership Team
• Head of Projects, AbbVie-Calico Leadership Team
• Specializes in medicinal chemistry and small molecule/ADC drug discovery
• Inventor of Foslevodopa/Foscarbidopa (ABBV-951) for the treatment of advanced Parkinson’s Disease
• Inventor of first-in-class PTPN2 phosphatase inhibitors ABBV-CLS-579 and ABBV-CLS-484 for the immunotherapy treatment of solid tumors
• Led teams that have produced 18 clinical development candidates across multiple therapeutic areas
• Active participant in ACS Pharma Leaders, ACS MEDI Long Range Planning Committee, National Medicinal Chemistry Organizing Committee, and Gordon Research Conference Chair, Natural Products
研究兴趣
论文共 137 篇作者统计合作学者相似作者
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David R. Hill, Alexander D. Huters,Timothy B. Towne,Rajarathnam E. Reddy,Jace L. Fogle,Eric A. Voight,Philip R. Kym
Chemical reviewsno. 23 (2023): 13693-13712
Richard S. Hong,Ana V. Rojas,Rajni Miglani Bhardwaj,Lingle Wang,Alessandra Mattei,Nathan S. Abraham, Kevin P. Cusack,M. Olivia Pierce,Sayan Mondal,Nada Mehio,Shailendra Bordawekar,Philip R. Kym,Robert Abel, Ahmad Y. Sheikh
Journal of Medicinal Chemistryno. 23 (2023): 15883-15893
Kathleen McGuire,Christina Baumgartner,Carey Backus,Rebecca Mathew,Kelly Klinge,Joseph Klahn,Prasanthi Geda,Kyle Halliwill, Jacqueline Aguado,Liang Mu,Ryan Duggan, Cara Hrusch,Elliot Farney,Zhaoming Xiong,Marinka Bulic,Patricia Trusk,Loren Lasko,Hakimeh Ebrahimi-Nik,Kathleen Yates,Robert Manguso, Keith Hamel,Marcia Paddock,Jennifer Frost,Philip Kym
Regular and Young Investigator Award Abstracts (2022)
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2022)
Matthew Rosebraugh,Eric A. Voight,Ehab M. Moussa,Feroz Jameel,Xiaochun Lou, Geoff G. Z. Zhang, Peter T. Mayer,Deanne Stolarik,Robert A. Carr, Brian P. Enright,Wei Liu,Maurizio F. Facheris,Philip R. Kym
A. K. Singh,Y. Fan,C. Balut,S. Alani,A. M. Manelli,A. M. Swensen,Y. Jia,T. R. Neelands, T. A. Vortherms,B. Liu, X. B. Searle,X. Wang,W. Gao, T-C Hwang,H. Y. Ren,D. Cyr,P. R. Kym,K. Conrath,C. Tse
Ashvani K. Singh, Y. Fan,C. Balut,S. Alani,A. M. Manelli,Andrew M. Swensen, Y. Jia,Torben R. Neelands,Timothy A. Vortherms,Liu Bo,Xenia B. Searle, X. Wang,Wenqing Gao, Tzyh Chang Hwang,H. Y. Ren,Douglas M. Cyr,Philip R. Kym,K. Conrath,C. Tse
Journal of Pharmacology and Experimental Therapeuticsno. 3 (2020)
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作者统计
#Papers: 138
#Citation: 6270
H-Index: 44
G-Index: 76
Sociability: 7
Diversity: 3
Activity: 3
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