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个人简介
My core research is directed at understanding how muscle satellite cells are regulated in healthy and diseased skeletal muscle and their roles in cancer. Skeletal muscle is an archetypal adult stem cell model, in which maintenance, growth and repair of functionally specialised post-mitotic cells is achieved by recruitment of undifferentiated precursors. The functional unit of a skeletal muscle is the myofibre: a giant syncytial cell maintained by hundreds of post-mitotic myonuclei. The routine needs for myonuclear homeostasis, together with the more sporadic demands for hypertrophy and repair, are performed by muscle satellite cells. These resident stem cells are normally mitotically quiescent in mature muscle, and so must first be activated to undergo extensive proliferation to generate myoblasts that eventually differentiate to provide new myonuclei. In muscle wasting diseases such as muscular dystrophies though, this regenerative capacity is gradually degraded.
研究兴趣
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HUMAN MOLECULAR GENETICSno. 2 (2024): 182-197
Juan Diego Hernandez-Camacho,Cristina Vicente-Garcia, Lorena Ardila-Garcia, Ana Padilla-Campos,Guillermo Lopez-Lluch,Carlos Santos-Ocana,Peter S. Zammit,Jaime J. Carvajal, Placido Navas,Daniel J. M. Fernandez-Ayala
Thuy-Hang Nguyen, Lise Paprzycki,Alexandre Legrand,Anne-Emilie Declèves,Philipp Heher, Maelle Limpens,Alexandra Belayew,Christopher R. S. Banerji,Peter S. Zammit,Alexandra Tassin
Skeletal Muscleno. 1 (2023)
ACS Applied Polymer Materialsno. 11 (2022): 8193-8202
Huascar Pedro Ortuste Quiroga,Massimo Ganassi,Shingo Yokoyama,Kodai Nakamura,Tomohiro Yamashita,Daniel Raimbach, Arisa Hagiwara, Oscar Harrington, Jodie Breach-Teji,Atsushi Asakura,Yoshiro Suzuki,Makoto Tominaga,Peter S. Zammit,Katsumasa Goto
Cellsno. 3 (2022)
P Heher, M Ganassi,A Weidinger, EN Engquist, J Pruller,TH Nguyen,A Tassin, AE Declèves,K Mamchaoui,J Grillari,AV Kozlov,PS Zammit
biorxiv(2021)
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作者统计
#Papers: 88
#Citation: 5802
H-Index: 29
G-Index: 65
Sociability: 6
Diversity: 3
Activity: 18
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