My major research interests are in the basic mechanisms of primary headache disorders, such as migraine and cluster headache, in both experimental and clinical settings, and translating these insights into their better management.

I am the Director of the National Institute for Health Research - Wellcome Trust King’s Clinical Research Facility (CRF). The CRF provides dedicated facilities to support the delivery of externally-funded early translational, experimental medical research, including early-phase studies and early translational research studies that are nested within later-phase studies.

I lead the Biomedical Research Council Themes; Clinical Research Facility, and Pain and Headache. I am also the National Lead for Neurological Disorders for the Clinical Research Network, NIHR UK, a Trustee of the Organisation for the Understanding of Cluster Headache (OUCH UK) and Chair of the Scientific Programme Committee, Migraine Trust International Symposium. I also lead the Pain and Addictions theme at the NIHR Maudsley Biomedical Research Centre.