He is actively involved in several national and international multi-center studies, serving on the Executive Committees of the Multicenter AIDS Cohort Study and the AIDS Malignancies Consortium, and participating in Interlymph, an international consortium of researchers with an interest in the epidemiology and pathogenesis of lymphoma. In addition to this, he is on the external steering committee for the AIDS Cancer Specimen Resource, is a member of the advisory council for the California HIV Research Program and of the Human Stem Cell Research Advisory Committee, California Department of Health Services.
Areas of Interest:
We are interested in better understanding the role of immune dysfunction in the genesis and growth of human cancer. Current work is focusing on better defining the role of HIV infection-associated immune dysfunction in the development and growth of AIDS-associated cancers. Currently, much of our work is directed at determining how immune system factors associated with B cell hyperactivation, including the up-regulation of the expression of activation-induced cytidine deaminase (AID), and virus (EBV, HIV) infection, contribute to the molecular lesions that result in the genesis of B cell lymphoma.