Escalante Nichole K - Department of Immunology, University of Toronto

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Abstract 6716: DLL3 TriTCE Co-Stim: A Next Generation Trispecific T Cell Engager with Integrated CD28 Costimulation for the Treatment of DLL3-expressing Cancers

Peter Repenning,Desmond Lau, Diana C. Hernaez,Alec Robinson, Diego P. Escanda, Mariana Rocha, Begonia S. Moreno, John Zhang, Polly Shao,Nichole Escalante,Lisa Newhook, Purva Bhojane,Chayne L. Piscitelli,Paul A. Moore,Thomas Spreter Von Kreudenstein,Nina E. Weisser

Cancer Researchno. 6_Supplement (2024): 6716-6716

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Abstract 2633: Zanidatamab Zovodotin (ZW49) Induces Hallmarks of Immunogenic Cell Death and is Active in Patient-Derived Xenograft Models of Gastric Cancer

Stuart D. Barnscher,Andrea Hernández Rojas,Kevin J. Hamblett,Nichole Escalante

Cancer Researchno. 7_Supplement (2023): 2633-2633

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Abstract 2926: PROTECTTM, a Novel Trispecific Antibody Masking Platform with Integrated Immune Modulation Displays Unique Activity and Differentiated Modes of Action

Anna von Rossum,Genevieve Desjardins,Nichole Escalante,Wingkie Wong,Bryant Harbourne,Janessa Li, Begonia Silva Moreno, Prajwal Raghunatha, Richard Kunze, Madeline Fung,Florian Heinkel,Harsh Pratap,Kevin Haworth,Eric Escobar-Cabrera,Brandon Clavette,Surjit Dixit,Nina Weisser,Thomas Spreter von Kreudenstein

CANCER RESEARCHno. 7 (2023)

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1372 TriTCE Co-Stim: a Novel Trispecific T Cell Engager Platform, with Integrated CD28 Costimulation, Engineered to Widen the Therapeutic Window for Treatment of Poorly Infiltrated Tumors

Maya Poffenberger,Nichole Escalante,Diego Perez Escanda,Nina Weisser,Thomas Spreter von Kreudenstein,Lisa Newhook, Purva Bhojane, Peter Repenning,Desmond Lau, Polly Shao,Alec Robinson, Kesha Patel, Alexandra Livernois,Chayne L Piscitelli,Nicole Afacan

Regular and Young Investigator Award Abstracts (2023)

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1396 TriTCE CPI: a Novel Trispecifc T Cell Engager Platform with Integrated PD-1/PD-L1 Checkpoint Inhibition Engineered for the Treatment of Immunosuppressed Tumors

Matteo Zago, Yun Peng,Meghan M Verstraete,Maya Poffenberger, Veronica Luu, Brenda Ma,Nichole Escalante,Janessa Li,Diego Perez Escanda,Siran Cao, Edward Meier,Sifa Arrafi,Anna Von Rossum,Genevieve Desjardins,Nina Weisser,Thomas Spreter von Kreudenstein

Regular and Young Investigator Award Abstracts (2023)

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Structure of the IFNγ Receptor Complex Guides Design of Biased Agonists

Juan L. Mendoza,Nichole K. Escalante,Kevin M. Jude,Junel Sotolongo Bellon,Leon Su,Tim M. Horton,Naotaka Tsutsumi,Steven J. Berardinelli,Robert S. Haltiwanger,Jacob Piehler,Edgar G. Engleman,K. Christopher Garcia

Nature（2019）

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Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance

Kenny L Chan,Theresa H Tam,Parastoo Boroumand,David Prescott,Sheila R Costford,Nichole K Escalante,Noah Fine,YuShan Tu,Susan J Robertson, Dilshaayee Prabaharan,Zhi Liu,Philip J Bilan,Michael W Salter,Michael Glogauer,Stephen E Girardin,Dana J Philpott,Amira Klip

Cell reports（2017）

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NKT Cell–Deficient Mice Harbor an Altered Microbiota That Fuels Intestinal Inflammation During Chemically Induced Colitis

Thirumahal Selvanantham,Qiaochu Lin,Cynthia Xinyi Guo,Anuradha Surendra,Stephanie Fieve,Nichole K. Escalante,David S. Guttman,Catherine J. Streuther,Susan J. Robertson,Dana J. Philpott,Thierry Mallevaey

JOURNAL OF IMMUNOLOGY（2016）

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