Through my training, I developed broad expertise on the crosstalk among liver cells on the fibrogenic response to liver injury, which continues to be the major focus of my research.
Thus, I have a long-standing interest in understanding the pathophysiology of liver fibrosis. I have significant experience with various models of liver fibrosis, primary cell isolation, cocultures of hepatocytes, Kupffer cells and hepatic stellate cells and the molecular biology and signaling pathways involved in collagen-I regulation. Upon my arrival to The University of Illinois at Chicago, I started the Extracellular Matrix Biology and Liver Research Program that built a network of scientists within our institution with common research interests.