Professor Ohuchi covers many reseach fields including oncology, surgery, molecular biology and cancer screening with more than 400 original articles. In summarizing activities as a chief investigator or chairman, the following will be selected, e.g., National breast cancer screening programs by Ministry of Health Labour and Welfare (MHLW,1995-present), Nano-biotechnology projects by MHLW (2002-08) and by Ministry of Education, Culture, Sports, Science and Technology (MECSST 2002-11) and by New Energy and Industrial Technology Development Organization (NEDO). He also organized the NIH-Japan-JSPS Symposium in Sendai, Japan 2013, and in Bethesda, USA 2014.

The Japan Strategic Anti-cancer Randomized Trial (J-START) is one of his representative projects which was supported by MHLW 2007-14, by AMED 2015-present. The primary endpoints of J-START assesed the efficacy of mammography with adjunctive ultrasonography in improving sensitivety and detection rates of early breast cancers in the Lancet, 387: 341-348. 2016