RESEARCH ACTIVITY - Glutathione and antioxidant enzymes in the control of reactive oxygen and nitrogen species metabolism and their alterations in redox-related pathologies (cancer, degeneration, Type 2 diabetes, atherosclerosis); - Nitric oxide metabolism and regulation of nitric oxide synthases; - Interplay between redox and phosphorylative signaling in tumor, neuronal cell death and viral infections; - Redox signal transduction pathways in cell processes (proliferation, differentiation, autophagy, apoptosis); - Control of mitochondrial function and turnover (biogenesis/mitophagy); - De-regulated metabolism (lipid, amino acids, glucose) of cancerous cells; - Impact of nutrients and nutraceuticals (polyphenols and organosulfur compounds) on redox homeostasis, epigenetics and cellular oxidative metabolism.