Morris White investigates the molecular basis of insulin signal transduction to understand the pathophysiology of diabetes and other disorders, including obesity, infertility, and cardiovascular and retinal diseases. His studies of the insulin-signaling network reveal common elements that promote peripheral insulin action, pancreatic beta-cell growth and function, and hypothalamic control of nutrient homeostasis and fertility. His work may reveal new strategies to treat dysregulated nutrient metabolism and type 2 diabetes.