Primary fields of research
Various biological barriers act as gatekeepers for successful drug delivery to the brain; e.g. the blood-brain barrier, the nose-to-brain barrier, and the blood-cerebrospinal fluid barrier.
I study strategies to overcome these barriers for brain drug delivery purposes using state-of-the-art cell culture models, to improve understanding of cellular pathways involved, as well as animals for pharmacokinetic- and pharmacodynamics profiling. Ultimately, this knowledge will be beneficial in the making of new drugs for the treatment of brain diseases.