Michael Sagmeister

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个人简介

His research project focuses on the role of cortisol metabolism in skeletal muscle tissue by the enzyme 11-beta hydroxysteroid dehydrogenase type 1 and uses pre-clinical models of kidney disease.

研究兴趣

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BS24 Establishing a Clinically Relevant Progressive Model of Ckd-Associated Cardiomyopathy in Mice for Insights into Early-Stage Pathogenesis

Abbie Hayes, Katie Bruce,Michael Sagmeister,Jonathan Townend,Charles Ferro,G. Andre Ng,Christopher O’Shea,Rowan Hardy,Davor Pavlovic

Basic science (2024)

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Renal 11[Beta]-Hydroxysteroid Dehydrogenase Type 2 is of Central Importance for 11-Oxygenated Androgen Biosynthesis and is Disrupted in Chronic Kidney Disease

Maria Tomkins,Tara McDonnell,Leanne Cussen,Sagmeister Michael S, Imken Oestlund,Fozia Shaheen,Lorraine Harper,Hardy Rowan S,Taylor Angela E,Gilligan Lorna C,Wiebke Arlt,Marie McIlroy,Freitas Declan de,Peter Conlon,Colm Magee,Mark Denton,Conall O'Seaghdha,Jacky Snoep, Karl Heinz-Storbeck,Mark Sherlock,O'Reilly Michael W

Endocrine Abstracts (2024)

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Impaired 11Β-Hydroxysteroid Dehydrogenase Type 2 Activity in Kidney Disease Disrupts 11-Oxygenated Androgen Biosynthesis

Maria Tomkins,Tara McDonnell,Leanne Cussen,Michael S Sagmeister, Imken Oestlund,Fozia Shaheen,Lorraine Harper,Rowan S Hardy,Angela E Taylor,Lorna C Gilligan,Wiebke Arlt,Marie McIlroy,Declan de Freitas, Peter Conlon,Colm Magee,Mark Denton, Conall O'Seaghdha,Jacky L Snoep,Karl-Heinz Storbeck,Mark Sherlock, Michael W O'Reilly

The Journal of clinical endocrinology and metabolism (2024)

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Glucocorticoid Excess Alters Metabolic Rate and Substrate Utilisation Via 11Β-Hsd1

Samuel R Heaselgrave,Silke Heising,Stuart A Morgan,David M Carthwright,Michael Sagmeister,Rowan S Hardy,Craig L Doig,Nicholas Morton,Kostas Tsintzas,Gareth G Lavery

The Journal of endocrinologyno. 2 (2024)

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Cortisol Excess in Chronic Kidney Disease - A Review of Changes and Impact on Mortality

Michael S. Sagmeister,Lorraine Harper,Rowan S. Hardy

FRONTIERS IN ENDOCRINOLOGY（2023）

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SAT276 Glucocorticoid Excess Elevates Metabolic Rate Via A 11B-Hsd1 Dependent Mechanism in C57BL/6J Mice

Samuel Heaselgrave,Silke Heising,Stuart Morgan,Ali Kabli,Michael Sagmeister,Craig Doig,Rowan Hardy,Nicholas M. Morton,Kostas Tsintzas,Gareth G. Lavery

Journal of the Endocrine Societyno. Supplement_1 (2023)

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Modelling Muscle Wasting in Chronic Kidney Disease under Conditions of Acidosis and Steroid Exposure

Alisha Hussain, Rania Dinouri,Ana Crastin,Michael Sagmeister,Rowan Hardy

Endocrine abstracts (2023)

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The Contribution of Glucocorticoid Metabolism by 11[Beta]-Hsd1 Towards Muscle Wasting in Chronic Kidney Disease

Ben Cassidy, Louise Firkins,Michael Sagmeister,Ana Crastin, Gowsihan Poologasundarampillai,Lorraine Harper,Jones Simon W.,Hardy Rowan S.

Endocrine Abstracts (2023)

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Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and Challenges

Thomas A Nicholson,Michael Sagmeister,Susanne N Wijesinghe,Hussein Farah,Rowan S Hardy,Simon W Jones

Pharmaceuticsno. 1 (2023)

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The Role of Glucocorticoid Metabolism in the Skeletal Pathophysiology of Chronic Kidney Disease

Anil Shanker, Ben Cassidy,Ana Crastin,Gowsihan Poologasundarampillai,Rowan Hardy,Lorraine Harper,Simon W. Jones,Michael Sagmeister

Endocrine abstracts (2023)

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Clinical Research Fellow

论文共 28 篇作者统计合作学者相似作者