Michael G Jobling

My interests involve the pathogenesis of diarrheal diseases caused by Vibrio cholerae and enterotoxigenic Escherichia coli (ETEC), by studying the genetics, structure and function of cholera toxin (CT), a prototypical A-B5 ADP-ribosylating toxin, and the related heat-labile enterotoxins (LT) of ETEC. We also have an interest in using these toxins as adjuvants for vaccines against diarrheal diseases and have recently discovered novel pertussis-toxin like toxins in type II ETEC.