His main focus is the use of autologous MSCs and mechanoregulation for the repair of musculoskeletal tissues using a cell therapy approach. To this aim he investigates novel cell identification and isolation methods. His research interests include the mechano-regulation of progenitor cell fate, in particular chondrogenic differentiation. This has led to advances in regenerative rehabilitation and the discovery of novel clinically relevant biomarkers and targets. He is also interested in the mechanisms by which progenitor cells direct cell fate and interact with endogenous cells to effect a repair.
He is the author of over 130 scientific papers and book chapters, is the editor of two books and has 2 accepted patents. He is the chair of the LearnORS Committee of the ORS, member of the TERMIS EU Meeting and Sponsorship Committee, member of the International Consortium for Regenerative Rehabilitation Leadership Council, and the deputy co-chair of the ICRS Basic Science Committee. He is an editor or associate editor for five journals, including Associate Editor, Frontiers in Bioengineering and Biotechnology and scientific editor for eCM Journal. He is the conference chair of the yearly eCM Conference.