Manjunath directs the Center for Multimodal Big Data Science and Heathcare. He has published over 300 peer-reviewed articles in various journals and peer reviewed conferences and his publications have been cited extensively. He is an inventor on 24 Patents and co-edited the first book on the ISO/MPEG-7 multimedia content representation standard. He directed the NSF/ITR supported center on Bio-Image Informatics. His team is developing the open-source BisQue image informatics platform that helps users manage, annotate, analyze and share their multimodal images in a scalable manner with a focus on reproducible science.