I am developing our activities and research portfolio in planetary health informatics: data science solutions to address environmental challenges. We strive to build capacities in coordinating biodata resources and developing data science tools and services that contribute to planetary preservation and restoration by addressing the global crisis and delivering direct benefits for society. We focus on genomics data as part of developing the broader biodiversity knowledge graph to connect and integrate diverse data types for enhanced understanding and monitoring of the health of species and ecosystems. We are deeply involved in coordinating and leading European efforts for scaling up production of biodiversity genomics data and building data management infrastructures required for efficient processing and open data sharing. The research focus is on downstream analyses: data science methods for developing the computational biology tools required to make sense of the molecular data in the context of connected knowledge, extracted from the scientific literature, or from species and environment observation and monitoring data, or from natural history collections and trait information. By meeting key needs in data collection, integration, and analysis, we aim to facilitate the development of informatics tools and services to support data-driven, empirically informed, and model-guided policies and actions addressing environmental challenges.