Prof. Vallet-Regí has been awarded many important International prizes and she is member of the Spanish academies of Pharmacy, Engineering, European of Doctors, and the International College of Fellows of Biomaterials Science and Engineering (FBSE) and the American Institute for Biomedical and Biological Engineering (AIMBE).

Prof. Vallet-Regí is widely regarded for her contributions to Biotechnology and Medicine. A recent report released by Standford University has included her among the 2% of the top researchers in the World. The database, that analyses the career long impact by researchers according to Scopus database, has been published in PLoS Biology in 2020 and ranks her in the top position among Spanish colleagers and within th elite among World Researchers. In the updates of 2021,2022 and 2023 she continues been the first female spanish scientist. Moreover, she is a Highly Cited Researcher 2018 (Clarivate Analytics). This list recognizes world-class researchers selected for their exceptional research performance, demonstrated by production of multiple highly cited papers that rank in the top 1% by citations per field and year in Web of Science. She is recognized as a pioneer in the field of ceramic materials applied to medicine. On one hand, she has been working in the biomaterials area developing bioceramics for bone grafting applications and scaffolds for regenerative biomedicine. On the other hand, prof. Vallet-Regí has intensely investigated on nanocarriers of different nature to deliver therapeutic agents to diseased tissues without affecting healthy organs. She was the pioneer who suggested introducing drugs into the pores of mesoporous silica materials, which inspired thousands of publications worldwide involving mesoporous silica nanoparticles for drug delivery.