The Microbial Proteomics Group develops novel mass spectrometric approaches and data processing pipelines to explore the remarkable diversity of microbes and their communities they live in. Prokaryotes—the unseen majority on our planet—encompass an enormous metabolic and biochemical diversity. However, only a small fraction of this potential has been discovered and explored for their use in biotechnology to date (e.g., novel enzymes or valuable compounds). Our laboratory is equipped with micro- and nano-flow chromatographic systems coupled to state-of-the-art high-resolution mass spectrometers (GC-MS and LC-Orbitrap-MS instruments).