基本信息
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Bio
A long-term interest of the Hilton lab is to uncover the molecular circuitry regulating lineage commitment, proliferation, and differentiation of skeletal stem cells, chondrocytes, and osteoblasts. My laboratory uses genetic mouse models and primary cell culture techniques coupled with biochemistry to answer questions regarding skeletal stem cell self-renewal/differentiation, chondrogenesis, and osteoblastogenesis. Recently my lab has generated novel data from a variety of Notch gain and loss-of-function mutant mice demonstrating the importance of Notch signaling in each of these processes. We are currently investigating the exact Notch signaling mechanisms at play during skeletal development, disease, and repair. Additional studies are also focused on identifying and understanding the molecular mechanisms underlying various congenital skeletal pathologies, including Multiple Herediatry Exostoses (MHE) and Preaxial Polydactyly (PPD).
Research Interests
Papers共 124 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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期刊级别
合作者
合作机构
Journal of shoulder and elbow surgeryno. 4 (2024): e215-e222
Chang‐Lung Lee, Kennedy D. Brock, Stephanie Hasapis, Dadong Zhang,Alexander B. Sibley,Xiaodi Qin, Jeremy S. Gresham, Isibel Caraballo,Lixia Luo,Andrea R. Daniel,Matthew J. Hilton,Kouros Owzar,David G. Kirsch
openalex
Cellsno. 7 (2023): 981-981
Wendi Guo,Jiaul Hoque,Carolina J Garcia Garcia,Kassandra V Spiller,Abigail P Leinroth,Vijitha Puviindran, Cahil K Potnis, Kiana A Gunn,Hunter Newman,Koji Ishikawa,Tara N Fujimoto, Denae W Neill,Abagail M Delahoussaye,Nerissa T Williams,David G Kirsch,Matthew J Hilton,Shyni Varghese,Cullen M Taniguchi,Colleen Wu
Science translational medicineno. 724 (2023): eabo5217-eabo5217
eLife (2022)
Magnetic resonance imaging (2022): 243-250
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Author Statistics
#Papers: 124
#Citation: 5490
H-Index: 37
G-Index: 73
Sociability: 6
Diversity: 3
Activity: 25
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