My internationally recognized research program examines the biological mechanisms underpinning the decline in cardiovascular health and fitness across the healthy aging and heart failure continuum, and the role of lifestyle interventions to improve cardiac, peripheral vascular, and skeletal muscle function, physical function and quality of life. A second research area is in the cardiooncology field with specific focus on the role of exercise training to prevent cardiovascular and skeletal muscle deconditioning across the breast cancer survivorship continuum. A final research focus is in sport cardiology and cardiac mechanics in athletes.