My research in exposure and risk assessment modelling focuses on uptake and effects of contaminants in aquatic organisms under realistic exposure scenarios. What is the influence of environmental and physiological factors and how can we predict these? How do findings from the lab translate to the field situation? What are the relevant parameters in the field, e.g. during flood events or as a result of global change? To answer these and other questions, I use computational models that are informed by experimental data and combine knowledge from different fields, including toxicology, environmental chemistry, and hydrology.