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The aim of Miguel’s research programme is understanding the cellular and molecular mechanisms that mitochondria use, as signaling hubs, for coping with toxic insults. We aim to manipulate these signaling mechanisms to protect tissues such as heart, liver and the brain from toxicity following exposure and in disease conditions. Thus, this is a cell biology-based programme that aims to provide detailed, applicable, mechanistic toxicology, to identify the molecular initiating events and downstream toxicity pathways, associated with loss of mitochondrial function, that are disease relevant.
The aim of Miguel’s research programme is understanding the cellular and molecular mechanisms that mitochondria use, as signaling hubs, for coping with toxic insults. We aim to manipulate these signaling mechanisms to protect tissues such as heart, liver and the brain from toxicity following exposure and in disease conditions. Thus, this is a cell biology-based programme that aims to provide detailed, applicable, mechanistic toxicology, to identify the molecular initiating events and downstream toxicity pathways, associated with loss of mitochondrial function, that are disease relevant.
Research Interests
Papers共 126 篇Author StatisticsCo-AuthorSimilar Experts
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Emma L. Wilson,Yizhou Yu, Nuno S. Leal,James A. Woodward,Nikolaos Patikas,Jordan L. Morris,Sarah F. Field, William Plumbly,Vincent Paupe,Suvagata R. Chowdhury,Robin Antrobus,Georgina E. Lindop,
Cell Death & Diseaseno. 3 (2024): 203-203
Emma L. Wilson,Yizhou Yu, Nuno S. Leal,James A. Woodward,Nikolaos Patikas,Jordan L. Morris,Sarah F. Field, William Plumbly,Vincent Paupe,Suvagata R. Chowdhury,Robin Antrobus,Georgina E. Lindop,
CELL DEATH & DISEASEno. 3 (2024)
Research Square (Research Square) (2023)
Biology directno. 1 (2023): 43-17
Scientific reportsno. 1 (2023): 20616-20616
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Niall Buckley,Andrew Craxton,Xiao-Ming Sun,Emanuele Panatta,Lucia Pinon, Jaime Llodrá, Nobuhiro Morone,Ivano Amelio,Gerry Melino,L. Miguel Martins,Marion MacFarlane
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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