Liling Wan

基本信息

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职业迁徙

个人简介

Research Interests:
The research interests in the Wan Lab lie in the intersection of cancer biology and epigenetics.

研究兴趣

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Dysregulation of Transcriptional Condensates in Human Disease: Mechanisms, Biological Functions, and Open Questions

Kaeli M Mathias,Yiman Liu,Liling Wan

Current Opinion in Genetics & Development (2024): 102203

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Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable in Vivo Studies: Discovery of TDI-11055

Mayako Michino,Tanweer A. Khan,Michael W. Miller,Yoshiyuki Fukase,Jeremie Vendome,Carolina Adura,J. Fraser Glickman,Yiman Liu,Liling Wan,C. David Allis,Andrew W. Stamford,Peter T. Meinke,Louis M. Renzetti,Stacia Kargman, Nigel J. Liverton,David J. Huggins

ACS MEDICINAL CHEMISTRY LETTERSno. 4 (2024): 524-532

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Condensate-promoting ENL Mutation Drives Tumorigenesis in Vivo Through Dynamic Regulation of Histone Modifications and Gene Expression

Yiman Liu,Qinglan Li,Lele Song,Chujie Gong,Sylvia Tang,Krista A. Budinich,Ashley Vanderbeck, Kaeli M. Mathias,Gerald B. Wertheim,Son C. Nguyen,Riley Outen,Eric F. Joyce,Ivan Maillard,Liling Wan

CANCER DISCOVERY（2024）

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Single-cell Multiomics Reveals ENL Mutation Perturbs Kidney Developmental Trajectory by Rewiring Gene Regulatory Landscape

Lele Song,Qinglan Li,Lingbo Xia, Arushi Eesha Sahay,Qi Qiu,Yuanyuan Li,Haitao Li,Kotaro Sasaki,Katalin Susztak,Hao Wu,Liling Wan

NATURE COMMUNICATIONSno. 1 (2024)

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Single-Cell Multiomics Reveals ENL Mutation Perturbs Kidney Developmental Trajectory by Rewiring Gene Regulatory Landscape

Lele Song,Qinglan Li,Lingbo Xia, Arushi Sahay,Qi Qiu,Yuanyuan Li,Haitao Li, Kotaro Sasaki,Katalin Susztak,Hao Wu,Liling Wan

bioRxiv (Cold Spring Harbor Laboratory) (2024)

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Investigating the impact of hotspot mutations in a chromatin reader on leukemogenesis

Yiman Liu,Qinglan Li,Sylvia Tang,Chujie Gong,Liling Wan

CANCER RESEARCHno. 7 (2023)

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Supplementary Table S4 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

Xue Qing David Wang,Dandan Fan,Qinyu Han,Yiman Liu,Hongzhi Miao,Xinyu Wang,Qinglan Li,Dong Chen,Haley Gore,Pamela Himadewi,Gerd P. Pfeifer,Tomasz Cierpicki,Jolanta Grembecka,Jianzhong Su,Shasha Chong,Liling Wan,Xiaotian Zhang

crossref（2023）

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Charles David Allis (1951-2023) Obituary

Ping Chi,Peter W. Lewis, Chao Lu,Janice Lu,Alexander J. Ruthenburg,Benjamin R. Sabari,David Shechter,Liling Wan,Gang Greg Wang

NATURE GENETICSno. 4 (2023): 522-523

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Supplementary Table S3 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

crossref（2023）

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论文共 45 篇作者统计合作学者相似作者