My primary long-standing research interest has been to define molecular and cellular mechanisms underlying synaptic plasticity, learning and memory.

Recent achievements and ongoing work in the lab involves elucidating how alteration of neurotrophin signalling and/or other molecules of interest in specific neurons affects the development of neural circuits and contribute to cognitive disorders, basal ganglia movement disorders, or to metabolic dysfunctions.

Lately, to break new ground in the understanding of neuronal function and associated pathologies, we have established single cell transcriptome analysis of adult neurons. This technology is particularly useful for the identification of molecular and functional heterogeneity within cell populations currently believed to be homogeneous.