Her academic training is in mathematics and statistics, and she has been involved in genetic studies since her PhD. She co-chairs the Psychiatric Genomics Consortium Major Depressive Disorder Working group and is Co-Deputy Lead of the Trials, Genomics and Prediction theme at the NIHR Maudsley Biomedical Research Centre. Her multi-disciplinary research group identifies and characterises genetic variants conferring risk of disease, including depression, schizophrenia, and stroke. A major focus is a risk assessment, determining how the polygenic component of mental health disorders can be measured accurately and used in clinical care.