Levon heads the Vascular Biology and Translational Research Laboratory within the School of Medical Sciences, UNSW Faculty of Medicine. His research program sits within UNSW Medicine’s Thematic Areas of Cardiovascular and Cancer Biology, and has two major objectives:

To better understand how potentially harmful genes are controlled in vascular cells. This arm investigates signalling and transcriptional mechanisms of growth factor and pro-inflammatory cytokine-dependent gene expression, post-translational mechanisms that modify protein behaviour, isolation and characterization of new genes that are induced or repressed by acute vascular cell injury, and the molecular control of vascular cell migration and proliferation. The group has considerable expertise in preclinical models of cardiovascular disease and cancer
To develop novel vascular therapeutic agents for cardiovascular and inflammatory disease, tumour growth and metastasis. The lab is harnessing the outcomes of its fundamental research by pioneering the development of novel anti-gene, gene-therapeutic and small molecule pharmacological strategies targeting regulatory genes in experimental vascular diseases. This involves in-house laboratory research and strategic national and international collaborations with a range of clinical and preclinical specialists, global contract research organisations, leading industrial medicinal chemists and drug development consultants.