Leora Horn

基本信息

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职业迁徙

个人简介

I lead the company’s global research and development in lung cancer, a disease that despite many gains in recent years, remains the most common cause of cancer related mortality around the world. In my role, I partner with lung cancer teams from across AstraZeneca Oncology to rapidly progress our research and deliver on our commitment to cure more patients with the disease.

研究兴趣

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A Phase 1/2 Study to Evaluate the Safety and Activity of Nivolumab in Combination with Vorolanib, a Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitor, in Patients with Refractory Thoracic Tumors

Kathryn E. Beckermann,Christine M. Bestvina,Badi El Osta,Rachel E. Sanborn,Hossein Borghaei,Philip Edward Lammers,Giovanni Selvaggi,Jennifer G. Whisenant,Ellen Heimann-Nichols,Lynne Berry,Chih-Yuan Hsu,Yu Shyr,Leora Horn,Heather Wakelee

JTO Clinical and Research Reportsno. 2 (2024): 100619-100619

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Tumor-Naive Pre-Surgical Ctdna Detection is Prognostic in Stage I Lung Adenocarcinoma (LUAD), Associating with PD-L1 Positivity and High-Grade Histological Subtype

Tae Hee Hong,Soohyun Hwang, Chris Abbosh, Abhijit Dasgupta, Violeta Guthrie, Tiffany Hung, Jorg Bredno,Jill Walker, Xiaojin Shi,Tsveta Milenkova,Leora Horn, Joon Young Choi, Ho Yun Lee, Jong Ho Cho, Yong Soo Choi, Young Mog Shim,Darren Hodgson,Hong Kwan Kim, Myung-Ju Ahnl

JOURNAL OF THORACIC ONCOLOGYno. 7 (2024): E37-E37

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PP01.82 Tumor-Naïve Pre-Surgical Ctdna Detection is Prognostic in Stage I Lung Adenocarcinoma (LUAD), Associating with PD-L1 Positivity and High-Grade Histological Subtype

Tae Hee Hong, Soohyun Hwang,Chris Abbosh, Abhijit Dasgupta,Violeta Guthrie,Tiffany Hung,Jörg Bredno,Jill Walker,Xiaojin Shi,Tsveta Milenkova,Leora Horn, Joon Young Choi, Ho Yun Lee, Jong Ho Cho, Yong Soo Choi, Young Mog Shim,Darren Hodgson, Hong Kwan Kim, Myung-Ju Ahn

Journal of Thoracic Oncologyno. 7 (2024): e37

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Clinical Utility of Tumor-Naïve Pre-surgical Ctdna Detection in Early-stage NSCLC

Tae Hee Hong,Soohyun Hwang, Abhijit Dasgupta,Chris Abbosh,Tiffany Hung,Jörg Bredno,Jill Walker,Xiaojin Shi,Tsveta Milenkova,Leora Horn,Joon Young Choi,Ho Yun Lee,Jong Ho Cho,Yong Soo Choi,Young Mog Shim,Shoujie Chai,Kate Rhodes,Manami Roychowdhury-Saha,Darren Hodgson,Hong Kwan Kim

Journal of thoracic oncology official publication of the International Association for the Study of Lung Cancerno. 11 (2024): 1512-1524

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Phase 1/2 Trial of the XPO1 Inhibitor Selinexor in Combination with Docetaxel in Previously Treated, Advanced KRAS Mutant Non-Small Cell Lung Cancer (NSCLC)

Mitchell S. von Itzstein,Timothy F. Burns,Jonathan Dowell,Leora Horn,David Ross Camidge,Sally J. York, Keith D. Eaton,Christopher James Walker, Song Zhang,David E. Gerber

JOURNAL OF CLINICAL ONCOLOGYno. 16 (2024)

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Implementing Circulating Tumor DNA As a Prognostic Biomarker in Resectable Non-Small Cell Lung Cancer

Chris Abbosh,Darren Hodgson,Gary J. Doherty,Davina Gale,James R.M. Black,Leora Horn,Jorge S. Reis-Filho,Charles Swanton

Trends in cancer (2024)

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Afatinib and Necitumumab in EGFR-Mutant Non-Small Cell Lung Cancer with Acquired Resistance to EGFR Tyrosine Kinase Inhibitors

Nathaniel J. Myall, Jennifer G. Whisenant, Joel W. Neal, Wade T. Iams, Karen L. Reckamp, Sally York, Lynne D. Berry,Yu Shyr,Leora Horn, Heather A. Wakelee, Sukhmani K. Padda

JTO Clinical and Research Reports (2024)

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Tumor-naïve pre-surgical ctDNA detection is prognostic in clinical stage I lung adenocarcinoma