Dr. Yaffe is an internationally recognized expert in the epidemiology of dementia and cognitive aging and the foremost leader in identifying modifiable risk factors for dementia. Her research, currently supported by over a dozen NIH, Department of Defense, VA, and foundation grants, bridges the fields of neurology, psychiatry, and epidemiology. Dr. Yaffe was the first to determine that potentially 30% of dementia risk is preventable. She pioneered early investigations on the roles of estrogen, physical activity, and cardiovascular factors in dementia risk, and more recently, her research group has led work on the connections between cognitive aging and sleep disorders, traumatic brain injury and lifecourse exposures. With over 600 peer-reviewed articles dedicated to improving population brain health (H-index=152 and recognized by Clarivate Analytics as one of the most highly cited researchers in her field), her work has formed the cornerstone for dementia prevention trials worldwide. In recognition of these groundbreaking accomplishments, Dr. Yaffe received the Potamkin Prize for Alzheimer’s Research in 2017 and was elected to the National Academy of Medicine in 2019.