Innate Immunity and complement activation, Catecholamine, Cell permeability, Disseminated intravascular coagulation (DIC), Massive transfusion, Point-of-care testing (ROTEM, TEG, T-TAS) in severe trauma, sepsis, and any shock, Hepatic portal venous gas (HPVG), Anaphylactic shock, Haptoglobin, Antithrombin (AT), Open abdominal management (OAM), Dexmedetomidine, Continuous renal replacement therapy (CRRT), Acute respiratory distress syndrome (ARDS), FAST, Pre-hospital care.