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The goal of my research group is to understand the oncogenic mechanisms that cause malignant transformation of mature B cells and plasma cells.
Cancers of the B-cell lineage, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Thus, there is a clinical need for more effective therapies against these malignancies, which requires a better understanding of the biology of these cancers.
My laboratory focusses on the elucidation of the molecular mechanisms that govern the differentiation of B cells. We aim to understand how the disruption of these mechanisms by genetic mutations leads to the development of B-cell and plasma cell malignancies.
Cancers of the B-cell lineage, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Thus, there is a clinical need for more effective therapies against these malignancies, which requires a better understanding of the biology of these cancers.
My laboratory focusses on the elucidation of the molecular mechanisms that govern the differentiation of B cells. We aim to understand how the disruption of these mechanisms by genetic mutations leads to the development of B-cell and plasma cell malignancies.
Research Interests
Papers共 144 篇Author StatisticsCo-AuthorSimilar Experts
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Guilhem Lalle,Raphaëlle Lautraite,Khaled Bouherrou,Maud Plaschka,Aurora Pignata,Allison Voisin,Julie Twardowski,Marlène Perrin-Niquet,Pierre Stéphan, Sarah Durget,Laurie Tonon,Maude Ardin,Cyril Degletagne,Alain Viari, Laurence Belgarbi Dutron,Nathalie Davoust,Thomas S Postler,Jingyao Zhao,Christophe Caux,Julie Caramel,Stéphane Dalle,Philippe A Cassier,Ulf Klein,Marc Schmidt-Supprian, Roland Liblau,Sankar Ghosh,Yenkel Grinberg-Bleyer
The Journal of experimental medicineno. 6 (2024)
Frontiers in immunology (2024)
Journal of Immunologyno. 1_Supplement (2023): 168.03-168.03
Rebecca J. Brownlie,Ruth Kennedy,Erica B. Wilson,Maja Milanovic,Claire F. Taylor,Dapeng Wang,John R. Davies,Heather Owston,Emma J. Adams,Sophie Stephenson,Rebecca Caeser,Benjamin E. Gewurz,Peter Giannoudis,Claudio Scuoppo,Dennis Mcgonagle,Daniel J. Hodson,Reuben M. Tooze,Gina M. Doody,Gordon Cook,David R. Westhead,Ulf Klein
JOURNAL OF IMMUNOLOGYno. 1 (2023)
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Nature immunologyno. 8 (2023): 1217-1219
medrxiv(2023)
Bloodno. 4 (2022): 475-476
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Author Statistics
#Papers: 148
#Citation: 20345
H-Index: 57
G-Index: 106
Sociability: 6
Diversity: 3
Activity: 24
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