基本信息
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Career Trajectory
Bio
Microbes must cope with harsh, rapidly changing environments to survive. To do this, microbes have developed sophisticated mechanisms to (a) sense the changes in the environment, and (b) respond quickly to these changes to protect itself from harm or capitalize on an opportunity. Our lab seeks to rewire these fundamental input/output relationships to program cells to do useful things for mankind in a paradigm called synthetic biology. Inputs: We study methods to modify existing environmental detection sensors in yeast and modify them to detect new analytes. Outputs: We investigate ways microbes modify their metabolic networks and use these modifications to increase production of a given metabolite.
Synthetic biology offers a disruptive technology that has vast potential to impact the most important facets of our lives. The way we diagnose diseases, the drugs we use, the fuels we put in our cars, the plastic that is used in our potato chip bag – we have the opportunity to improve the sustainability of our lifestyle. And by reducing costs, we can make aspects of our lifestyle available to those who could not otherwise afford it. We hope to offer technical contributions that, simply put, make the world a better place.
Synthetic biology offers a disruptive technology that has vast potential to impact the most important facets of our lives. The way we diagnose diseases, the drugs we use, the fuels we put in our cars, the plastic that is used in our potato chip bag – we have the opportunity to improve the sustainability of our lifestyle. And by reducing costs, we can make aspects of our lifestyle available to those who could not otherwise afford it. We hope to offer technical contributions that, simply put, make the world a better place.
Research Interests
Papers共 95 篇Author StatisticsCo-AuthorSimilar Experts
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BIOTECHNOLOGY AND BIOENGINEERING (2024)
crossref(2024)
bioRxiv the preprint server for biology (2024)
ACS SYNTHETIC BIOLOGYno. 8 (2024): 2492-2504
Courtney K. Carlson,Theresa B. Loveless, Marija Milisavljevic, Patrick I. Kelly,Jeremy H. Mills,Keith E. J. Tyo,Chang C. Liu
ACS SYNTHETIC BIOLOGYno. 10 (2024): 3326-3343
Ashty S Karim, Dylan M Brown,Chloé M Archuleta, Sharisse Grannan,Ludmilla Aristilde,Yogesh Goyal,Josh N Leonard,Niall M Mangan,Arthur Prindle,Gabriel J Rocklin,Keith J Tyo, Laurie Zoloth,Michael C Jewett,Susanna Calkins,Neha P Kamat,Danielle Tullman-Ercek,Julius B Lucks
Nature communicationsno. 1 (2024): 5425-5425
bioRxiv : the preprint server for biology (2023)
Frontiers in microbiology (2023): 1287491-1287491
bioRxiv (2023)
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Author Statistics
#Papers: 94
#Citation: 2545
H-Index: 24
G-Index: 50
Sociability: 5
Diversity: 3
Activity: 24
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